One of the major projects initiated by FFS consists of building a shared biobank and a common clinical database: this will make it possible to identify biomarkers (genetic, epigenetic, endocrine, inflammatory, cognitive, etc.) associated with bipolar disorders, OCD, hyperactivity, borderline disorders, depression…

Biological samples from patients with reported diseases are grouped and analysed for research purposes. By sharing databases these are compared with data from subjects at risk and control groups.

The implementation of this biobank is complex, first of all it is necessary to bring the material together, obtain institutional and ethics committee authorisations and above all to ensure that the anonymisation of patient data is fully respected, thus ensuring full data security.


Development work takes place in several stages in order to first of all create the infrastructure that “hosts” the shared databases. Ultimately, it is a matter of setting up computerised records, centralising biological samples (DNA, RNA, serum, plasma, microbiota) in a common biobank from which they are processed and analysed. Another step is to fund the human resource requirements, tools and scientific equipment needed for sometimes very complex analyses of biological data from patients with reported disease, at-risk individuals and control groups.

Now, almost 2 years after the initiation of this project, the common database and shared biobanks are in place and functional. The correlation of the many clinical variables has been completed, which means that all the data collected on both sides are now’easily’ comparable. The competent authorities have recently validated the ethical protocol, which is an essential point because the security of medical data is once again, and rightly so, an extremely sensitive point. The next step, and this is the major objective for 2018, is to identify the patients for recruitment with bipolar disorder to participate in the study, in order to continue to enrich the biobanks and the database. The results of this initiative represent a potential for remarkable progress that is highly anticipated by the international scientific community.