Luc Mallet is a psychiatrist and neuroscience researcher. He was assistant clinical head in Psychiatry at the Henry Mondor teaching hospital in Créteil and subsequently at the Pitié-Salpêtrière teaching hospital in Paris. He worked during this time towards his Ph.D. thesis in functional medical imagery et the CEA (Atomic Energy Commission) after which he continued postdoctoral studies in Experimental Psychology at the CNRS (National Scientific  Research Centre).

In 2004 he took up a research post with the INSERM (Institut National de la Santé et de la Recherche Medicale) where he was subsequently promoted to Research Director in 2009 for behavioural studies on DBS (Deep Brain Stimulation) and the development of novel psychiatric therapies. Since 2008 he has directed the BEBG (Behaviour, Emotion and Basal Ganglia) research group at the Institut du Cerveau et de la Moelle épinière (ICM – Brain and Spinal Cord Research Institute) in Paris. This research programme aims to understand information processing within the Basal Ganglia in relation to psychopathology and to develop novel therapeutic solutions to severe and medically resistant mental disorders.

He coordinates in particular a number of interdisciplinary research projects aiming to characterise pathological repetitive behaviours in humans including OCD (Obsessive Compulsive Disorder). He is a member of numerous institutions for the promotion of psychiatric research, in particular as research director at the Fondation FondaMental in France.

In 2014, he was nominated to the chair of Psychiatry at the University of Paris-Est Créteil and to the post of associate professor at the Geneva University faculty of Medicine in 2013. He received the Marcel Dassault prize for mental health research in 2013 and the Philippe et Maria Halphen award from the Académie des Sciences in 2015.